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The Accelerate Pheno™ system in clinical practice: fast and accurate turnaround for critical results
Our clinical experiences of using the Accelerate Pheno™ system have greatly benefited patient care, providing earlier diagnostic certainty. Two complex sepsis cases are discussed, where the impact of rapid identification, with antibiotic sensitivities, of the causative organism from blood cultures is described. At Hampshire Hospitals NHS...
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Improving diagnostic stewardship by using new microbiological technologies
Describes an episode of sepsis in a leukaemia patient, whose treatment was early guided by using rapid diagnostics technology to identify the cause of infection. A 4-year-old patient under treatment for acute lymphoblastic leukaemia, diagnosed 6 months before, was admitted to the emergency room (ER) at midnight (00h33) due to a fever episode...
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Sepsis code implementation at Vall d’Hebron University Hospital: rapid diagnostics key to success
Implementation of a sepsis code, Código Sepsis, in October 2015 at the Vall d’Hebron University Hospital in Barcelona has led to better detection and a significant reduction in mortality. The hospital is the largest in Barcelona, with more than 1,100 beds and 7,000 employees. The objectives of Código Sepsis are to increase suspicion of sepsis and...
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Current challenges in paediatric sedation
Report of the Primex Pharmaceuticals Symposium, Euroanaesthesia 2017, Geneva, Switzerland, 4 June 2017 Current treatment options and challenges - Dr. K. Becke Background An increasing number of diagnostic and treatment procedures are performed outside the operating room. Without sedation even minor procedures such as vaccination...
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The Impact of Fast MIC Evaluation on Antimicrobial Stewardship: A Case Report
Dealing with Antimicrobial Resistance Recently antibiotic resistance has become a major public health issue with global dimensions, having a remarkable impact on morbidity, mortality and healthcare associated costs. Due to its increasing relevance, the “antibiotic resistance crisis” has entered the agenda of the WHO and other international...
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Current State of Glycaemic Control Practice
Elevated blood glucose is a widely recognised response to critical illness, with most non-diabetic patients exhibiting concentrations outside the normoglycaemic range and a substantial proportion having significantly or hugely elevated blood levels (Farrokhi et al. 2011). It has been 15 years since the publication of the Leuven study abruptly changed...
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Redesigning Emergency Ambulatory Care with Point-of-Care Testing: Reduced Costs and Length of Stay
Many patients presenting to the hospital emergency department do not need to stay overnight. Ambulatory emergency care (AEC) may optimise identification and management of such patients by delivering streamlined, efficient patient care within one working day. This may improve clinical outcomes, patient experience and lower costs. At James...
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Early Diagnosis and Prediction of Acute Kidney Injury
penKid – A Dynamic Inflammation-Independent Biomarker Of Kidney (Dys)function Early recognition and close monitoring of acute kidney injury (AKI) is vital in the ICU, given AKI’s high prevalence and effect on length of stay and risk of re-hospitalisation and death (McCullough et al. 2013). As more becomes known about biomarkers, intensivists need...
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Lung Protective Ventilation - Twinstream® Pulsatile Bi-Level Ventilation (P-BLV)
The Twinstream® ventilator (Carl Reiner GMBH, Vienna, Austria) is an electricdriven microprocessor-controlled jet ventilator, which allows simultaneous application of two different jet streams (low frequency and high frequency), resulting in a pulsatile Bi-Level Ventilation (p-BLV) mode. ICU Management & Practice spoke to Prof. Dr. Gerfried Zobel about...
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Rapid Pathogen Testing With PCR/ESI-MS In Practice
Kristoffer Strålin, MD, PhD , is Associate Professor and Senior Consultant at the Department of Infectious Diseases, Karolinska Institute, Stockholm, Sweden. Karolinska Institute is a world renowned medical university, which has the mission of improving people’s health through research and education. Together with Karolinska University Hospital,...
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Cognitive Impairment After Critical Illness: Prevention and Treatment
Why did you decide to investigate NTF-prep? Long-term cognitive impairment after critical illness (CIACI) was first described in 1999 (Hopkins 1999). In 1992 we noticed that in cardiac surgery with extracorporeal circulation patients there was a correlation between jugular bulb lactic acid and cognitive decline. We concluded that CIACI was a real...
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